The significance and relevance of the topic is justified by the current integration processes in the CIS, Customs Union of Russia, Kazakhstan and Belarus, as well as by the transition to a Common Economic Space. At the political level those processes are associated with the foundation of the Eurasian commission. It is possible that one of the Commission directions shall support cross-border cooperation and the development of cross-border regions (similar to the EU Euroregions). Round table discussion will concentrate on the economic prerequisites for such cooperation, analysis of mutual trade dynamics, industrial cooperation and integration, mutual cross-border investment of the Common Economic Space. Thus, the main focus of the discussion will be on the development of trade and industrial cross-border relations between Russia and Kazakhstan (based on the joint research of the Center for Integration Studies of the Eurasian Development Bank and the Leontief Centre).