Presentation of case studies of practical work in the field of cluster policy in the two regions of Russia. At present, in many regions of the Russian Federation the realization of cluster initiatives is in progress. So, in the last contest of Economic Development of Russia, it was announced to the implementation of more than 90 clusters. In this case, each region has its own special approach to their implementation. Practice identification, formation and development of clusters in Russia is just beginning to take shape and to regional authorities, companies participating in the cluster is essential to form the best practices implementation of cluster initiatives at all stages of the life cycle of the cluster. The target of this event is the formation of the practice.